Genomic Center - Projects

Projects  


INTERNATIONAL PROJECTS

PN-III-P3-3.1-PM-RO-CN-2018-0083 (Bilateral Cooperation Romania-China)

Experimental immunotherapy for haematological malignancie
Period 2018-2019

 

H2020-MSCA-RISE-2018- nr 824036

Excellence in research and development of non-coding RNA DIAGnostics in Oncology - RNADIAGON
Period 2018-2023

 

 

NATIONAL PROJECTS

CNFIS-FDI - CNFIS-FDI-2019-0666

“Sustenance and valorification of research of excellence in the domain of personalized medicine by internationalization and increasement of research activities visibility” – member

Period may 2019 – december 2019

PN-III-P1-1.1-TE-2016-2213 

“Targeting breast cancer resistance mechanism with combinatorial drug therapy using small molecules and siRNA, in post genomic era- DRUG_STORE

Period: 2018-2020

 

PN-III-P1-1.2-PCCDI-2017-0737 ctr. 35 PCCDI

Genomic population mapping of radioactive and heavy metals in order to increase national security - ARTEMIS
Period 2017 - 2020

PNCDI III 2015-2020 - Ctr. nr. 29PFE/18.10.2018

Increasing the performance of scientific research and technology transfer in translational medicine through the formation of a new generation of young researchers - ECHITAS
Period 2018-2020

 

POC-P_37_796 /2016 ctr 35/01.09.2016

Clinical and economic impact of personalized targeted therapies with anti - microARN in reconverting resistance of malignant lung tumors - CANTEMIR
Period: 2016-2020

POCU/380/6/13 - cod 125171

Academy of Researchers Entrepreneurs in Medicine
Period: 2019-2021

 

PN-III-P4-ID-PCE-2016-0795 

Addressing the complex exposome profile in hormone-dependent cancers of the breast and prostate and its influence on tumoral genome – ACHILLE
Period: 2017-2019 
 

COMPLETED PROJECTS

International Projects 

 H2020-WIDESPREAD-2016-2017 ID  763560 

Teaming Phase1 Romanian Centre of Excellence for Systems Immunology - ROCSI
Period: 2017-2018

 

PN-III-P1-1.1-BT-2016-0021 SEE-027 - 1 / 25.06.2015  

Innovative Nanoparticles-based  Chemotherapy  for Acute Myeloid Leukemia
Period: 2015-2016

PN-II-CT-RO-ZA-2014 – 1 ctr 7 BM/2016 (Bilateral Funding Romania- South Africa)

Use of new nanogold materials as delivery systems for modulation of MCL-1/p53 siRNA in ALL”- NanoLAL
Period: 2016 - 2017

American International School of Bucharest (TERRY FOX) ctr.1110/23.07.2015

MicroRNAs biomarkers of response to chemotherapy and overall survival in colon cancer 
Period: 2015-2016
 

57 BM/2016 Bilateral Funding (Beijing)

Non-invasive biomarkers for graft versus host disease following bone marrow hematopoietic stem cell transplantation
Period 2016-2017 

 

NATIONAL RESEARCH PROJECTS

PN-III-P1-1.1-MCT-2018-0006

Mobility Projects for Young Researchers from the Diaspora. Professor Guest: Dr. Gabriel Ghiaur
Period 2018

PN-III-P1-1.1-MC-2018-0195 MC

Mobility Projects for Researchers Ciprian Tomuleasa
Period 2018

FDI-2018-0262

Correlation of the educational offer in molecular medicine and translational onco-hematology with the demand on the labor market at European level
Period 2018

CNFIS-FDI-2017-1350

Modern training for healthcare professionals affiliated to the departments of hematology, oncology and bone marrow transplantation
Period 2017

FSS PROJECT

FSS Project to implement activities to identify and promote innovative student-initiated ideas, business ideas, entrepreneurship and student start-ups 2017
Period 2017


PN-II-RU-TE-2014-4-1783

“Massively parallel high-throughput DNA sequencing for the identification of microRNAs differentially expressed between the metastatic site and the tissue of origin in cancers of unknown primary site”
Period: 2015-2017
 
PN-II-RU-TE-2014-4-1464 ctr.307/2015
TGF β signaling pathway tapering: an alternative to TGFtarget breast cancer therapy
Period: 2015-2017
 

 PN-III-P1-1.1-MCD-2016-0049 MCD 

Mobility projects for researchers with experience from diaspora (Prof.Dr. George Adrian Calin)
Period 2016

PN-II-PT-PCCA-2013-4-2289 Ctr. 137/2014

Developing a method for real-time detection and isolation of circulating tumor cells from the bloodstream of cancer patients by means of image processing and pattern recognition - CTC VideoScop
Period: 2014- 2017
 
  

F-SEE Romania – European Economic Space (EES) cod F-SEE-003/07.2013 

Nanotechnology approach in Acute Myeloid Leukemia management” –   NanoLAM.  1 / 16.01.2014, 
Period 2014-2016
 
PN-II-PT-PCCA-2013-4-2166 ctr. 128/2014
 
New strategies for improving cancer patient’s quality of life and survival: molecular and clinical studies of cancer genome using depleted deuterium water model- GenCanD”
Period: 2014 - 2017
  

PN-II-PT-PCCA-2013-4-0030 ctr.196/2014 

Modulation of pro/anticarcinogenic effect of toxic chemical agents in breast cancer multitargeted therapy - CANCERTER-p53
Period:  2014- 2017  
 
PN-II-PT-PCCA-2013-4-1959 ctr.193/2014 Non-Invasive Intelligent Systems for Colorectal Cancer Diagnosis and Prognosis Based on Circulating miRNA Integrated in the Clinical Workflow – INTELCOR 
Period: 2014-2017
  
   
ESR-14-10102/17.10.2014 ASTRA ZENECA Ctr.ESR-14-10102/17.10.2014
BRCA1 and BRCA2 mutation analysis in Romanian population: a study of genotype-phenotype correlation at diagnosis with prospective disease outcome and survival”. 
Period: 2014-2016  

PN-II-PT-PCCA-2011-3.1-1221 Ctr. 125/2012  

Inteligent Systems of prediction of recurrence and progression in superficial bladder cancer based on artificial intelligence and microarray data: tumor mRNA and plasmatic microRNA - IntelUro 
Period:  2012 -  2016

PN-II-PT-PCCA-2011-3.2-1328 Ctr. 96/2012  

Analysis of microRNA biomarkers as predictive values for cervical cancer treatment, in relationship with environmental exposure to arsenic, phthalates and ETS - CERVICALL-ARSEN-ARRAY 
Period: 2012 -  2016

 

POSCEE 2010 nr. 709/12683 ctr. 228/06.08.2010 

Clinical and Economical Impact of the transcriptomic and proteomic molecular profile identification in the neoadjuvant therapy of triple negative breast cancer”-BREASTIMPACT
Period: 2010- 2014

FELLOWSHIP

Fellowship of the young researcher

Osan Ciprian-Ioan
Period 2017-2018

Program L’Oréal - UNESCO FOR WOMEN IN SCIENCE, Life Sciences Section- 4th edition (2012 - 2013), with a project entitled “Combining the chemotherapeutic effect of doxorubicin with RNA interference targeted therapy in the treatment of triple negative breast cancer” Cornelia Braicu
Period:2013-2014

 

INTERNAL GRANTS
 
Identifying a methylation profile of cancer-associated genes in squamous cell carcinoma 

Period: 2016-2018
 
MicroRNA analysis in breast cancer late apoptotic mechanisms Pileczki Valentina - 
Period 2014-2015

Cell and molecular mechanisms of primary myelofibrosis Tomuleasa Ciprian
Period 2014-2015

Circulating miRNAs as biomarkers for metastatic colorectal cancer - Petric Roxana
Period 2014-2015

INTERNAL GRANTS FOR STUDENTS

Target therapy in triple-negative breast cancer: evaluation of DNMT3b inhibition with nanaomycin A (students)
Period:2016-2018

 

A syntetic lethalaty approach in the acute myeloid leukaemia chemotherapy : PARP inhibitors plus anthreacycline plus decitabine vs anthreacycline plus decitabine – in vitro efficacy testing(students)
Period: 2016-2018

 

The efficacy of pirfenidone in the treatment of primary myelofibrosis (students)

Period: 2016-2018